Botulinum toxins, have been used in the treatment of disorders associated with muscle hyperactivity and orofacial pain and also for cosmetic purposes. It was off label use initially, but then it was confirmed in clinical trials, that patients treated with Botox reported additional nociceptive effects. The presumed mechanisms of action of the nociceptice effects of botulinum toxin will be discussed, along with the scientific evidence base for neurotoxin use in treating various TMD related and other Orofacial Pain conditions. A review of literature covering the use of neurotoxins to treat conditions such as bruxism, myofascial pain, recurrent TMJ dislocation, orofacial neuropathic pain and migraine headaches will be discussed.
General Practitioner: DDS(Toronto); MS(California); MDS(Prosthodontics-India); FICOI University of Toronto, Canada
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In life, you'll never find the answer to a question unless you're willing to ask it, as silly as it may seem..
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